The city of Potosí is connected with the main cities of the Bolivian territory by land. You can travel from La Paz by bus and get there in 10 hours.

For air connections, Sucre has an airport and you can get there from La Paz and Santa Cruz in about 45 minutes and from Cochabamba in 15 minutes, in domestic airlines, and then continue by land for 3 hours to Potosí.

There are transportation companies that can take you from the city of Villazón to Potosí, or from Uyuni by diesel railcar (express train).